About Us

About Us

Clinical-stage biotech company leveraging organoid- and AI-driven cancer drug discovery.

About Us

    Signet Therapeutics is a clinical-stage biotech company pioneering the development of first-in-class targeted cancer therapies using organoids and AI. The company has successfully secured nearly $31 million in funding and has been recognized in Forbes Asia 100 to Watch list. The company’s lead pipeline, SIGX1094, has entered Phase I clinical trials as a potential first-in-class targeted therapy for diffuse gastric cancer, a highly aggressive cancer with no approved targeted treatments. In addition to advancing its own pipeline, Signet`s organoid platform is available for external collaborations, providing innovative preclinical drug discovery and development services to biotech and pharmaceutical partners.

About Us

Founding Team

Innovative Drug R&D Pipeline

Innovative Drug R&D Pipeline

Organoid Disease Model Platform

Organoid Disease Model Platform

Company History

2025-02

The US FDA granted Fast Track Designation to SIGX1094.

2024-12

Raised over $9 million in Pre-A round financing and non-dilutive funding.

2024-11

The US FDA granted Orphan Drug Designation to SIGX1094.

2024-09

China's NMPA approved the IND application for SIGX1094.

2024-06

The FDA approved the IND application for SIGX1094.

2023-08

Selected as Forbes Asia 100 to Watch list.

2023-04

Established the first publicly accessible Organoid Disease Animal Center in Futian District, Shenzhen, China.

2022-02

Closed a $21 million angel round financing.

2020-12

SIGNET THERAPEUTICS was founded in Boston, U.S., with operations in Shenzhen, China.